Skip to Content

The Top Cat Kidney Disease Supplements

The Top Cat Kidney Disease Supplements

Supplements can be a great way of prolonging your cat’s life if they have kidney disease. We were able to keep one of our cats stable for 2 years before we lost him. The other has been in Stage 4 Kidney Failure for over a year and her values are actually improving! Now every cat is different so I can’t promise anything but the addition of supplements along with guidance from your vet is a great way to help manage this disease. Here are the top cat kidney disease supplements you can buy, no prescription required!

Benefits of Kidney Disease Supplements for Cats

Kidney Disease in cats means, well of course, that their kidneys are just no longer working up to par. The kidneys are responsible for filtering the waste out of our bodies when they aren’t working those toxins build up in the blood stream and don’t make your kitty feel so great.

Adding in supplements to your cat’s diet can help what function is left of the kidneys work better. In turn this should help your cat feel better and hopefully help keep your cat stable longer.

Supplement Options for Cats with Kidney Failure

Disclaimer: Before starting your cat on any supplements (just like you as human would) you should always consult with your vetrianan. They can confirm that it won’t interact with any of your cats medications or conditions. We also like letting our vet to review the brands ingredients for anything that wouldn’t be safe for cats. The FDA does not monitor any of these supplements, same with human supplements so it’s best to be safe. 

Omega 3

There are many options when hunting out an Omega 3. Our vet first recommended Nordic Naturals. It was pretty good and easy to give as it came in liquid so we mixed it right into his food. However the wonderful owner of the Facebook group I was mentioning earlier told me about Moxxor omega-3 and I had to give a try (spoiler it’s all we use in this house now). Moxxor has just 3 ingredients: greenlip mussle oil, kiwifruit seed oil and grapeseed oil. It’s simple yet powerful. Also if you have pet with seafood allergies you can still use this product since they remove.

A little more on all the rave around Greenlip Mussels. The New Zealand Greenlip Mussel contains a full spectrum of 18 omega-3’s, in contrast to a fractionated extract of just one or two omega-3’s. This unique source of omega-3 is absolutely pure and toxin-free. So now you can see why people are paying extra for this type of omega-3.

Omega-3 we Buy

B Vitamins

B12 is a great boost for cats with kidney issues. It is especially helpful for those cats battling anemia. We tried adminstering b12 shots here at the house but we just could be successful. Both our kidney cats screamed at us yet will tolerate subQ administering so clearly something is wrong on our end.

This led me to turn to a shot alternative. Dr. Mercola’s Vitamin B Complex for Dogs and Cats is a complete complex of the eight major B vitamins in their ideal proportions.

Because they are biologically active, this complex of vitamins can go to work in your pet’s body right away. Plus, they last longer than typical isolated vitamins.

Shop Vitamin B Complex

Kidney Restore

This is the most potent kidney supplement you can find anywhere that helps support their body’s kidneys in multiple different and unique ways. We were delighted to find after using this for about 3 months our cat went from a creatinine of 8 to 5! Note: She was also getting SubQ fluids as well.

Contains safe probiotic microorganisms (50 billion). They safely support elimination of harmful kidney toxins, and other dangerous waste by consuming them.

Kidney Restore For Cats & Dogs™ has prebiotics, a superfood for the probiotic microorganisms so they can continue to grow and multiply. The more microorganisms there are, the more nitrogenous (kidney toxic) waste they consume.

This amazing formula has a pinch of sodium bicarbonate. Sodium bicarbonate, a.k.a. baking soda is the most effective natural supplement that neutralizes the harmful acids that build up in weak kidneys.

Just a pinch this fantastic nutrient prevents acid buildup and has zero effects on other mineral levels.

When the kidneys become weak, phosphorous and cholesterol levels begin to rise. This formula contains Niacinamide, also known as Vitamin B3. It works wonders to balance phosphorus and support healthy lipid levels. B3 also supports heart health.

Kidney Restore For Cats & Dogs™ has vitamin C from the Peruvian superfood camu-camu. This berry contains 23 times more Vitamin C than an orange. Vitamin C is the most potent antioxidant helping your pet’s body to neutralize free radicals, especially in the kidneys.

No remedy will work if your pet doesn’t take it. That’s why Kidney Restore For Cats & Dogs™ is bacon flavored. Just add a sprinkle on their food and even finicky cats will eat it. Both my cats we use this one LOVE we add this to their food.

Shop Kidney Restore

Pet Wellbeing Kidney Support Gold

One of the first supplements that was recommended to me was Kidney Support Gold. Kidney Support Gold for Cats is a powerful herbal formula designed to support renal function and overall health for kidney issues in cats. This formula is created by using current research with time-honored herbs used in traditional Asian medicine for the kidneys. The herbs in Kidney Support Gold are restorative, help maintain vitality, and provide absorbent nutrition to the body to support both acute and chronic kidney disease in cats. Overall, our herbal formula helps the body regulate the immune system and respond normally to bacteria and viruses in a way that is holistic. 

We gave this a go but unfortunately after a week or so we noticed it was giving our guy dihaerra so we had to stop use. Most people have no side effects and SWEAR by the magic of this supplement. However, it’s always a good idea when starting anything to closely monitor your cat. A bonus of ordering from Amazon is they have a money back guarantee so if it doesn’t help or you cat has a reaction you can always return.

If your cat isn’t a fan of things added to your food you could try treats from Scruffy Paws Kidney Vitalize Chews. Its two main ingredients match that of Kidney Support Gold while I will say it does look as though there is added ingredients of the Kidney Support Gold not found in these chews.

Buy Kidney Support Gold


AminAvast is a nutritional supplement composed of amino acids and a peptide formulated to support kidney health and function. Dogs and cats can take AminAvast for the full duration of their lives. No side effects have been reported when using AminAvast for both short-term or long-term use.

Customers who have given their pet AminAvast have reportedly seen benefits within weeks of starting AminAvast.

This product is similar to the Kidney Restore & Azodyl where it is a mix of probiotics that help reduce the load of waste on the kidneys. Essentially making it so their kidneys don’t have to work as hard.

Shop AminAvast


Azodyl is a breakthrough supplement that supports kidney function in dogs and cats. Azodyl contains a blend of naturally-occurring friendly bacteria (commonly known as probiotics) that can help support kidney function. Basically these magical strains of bacteria feed off of the waste buildup that is happening in your cat’s body and help them feel better.

The downside to this one, it’s a pill and while it is small it must be swallowed whole. Pill pockets on this size didn’t seem to work on our cat so we had to get creative. I crush pure bits (shrimp and duck are his weakness) and mix the pill in with that and he thankfully is so excited for the treats he gobbles them down along with the pill. If you cat is receptive to being pilled that is always an option too.

Shop Azdoyl

NOTE: This medicine needs to stay refrigerated to keep the bacteria alive. It is pricey so don’t be a fool and leave it out on the counter like me.

Astro’s Oil

This is a newer product that I discovered and it has a cult following of people who swear by it.  It contains Omega 3 fish oil concentrate that has been molecularly distilled via freeze fracturing to purify it of all pollutants such as heavy metals and PCB’s.

It is designed to address inflammation of kidney tissue which can help restore function to the affected tissue before it progresses to cicatrization (scarring) with permanent loss of kidney function.

Order Astro’s Oil


Okay before you get all skeptical, cause I was when this was recommended, yes this is legal in all 50 US States. The brand we use, CBD Pet, contains extremely small amounts of the THC cannabinoid. This is good and key when shopping brands because THC is unhealthy to both cats and dogs in large doses. This helps ease any fears of “overdosing” animals using CBDPet. Their oil is batch-tested to ensure THC levels remain far below 1%.

Here are just some of the things that CBD oil can help with:

  • Appetite
  • Anxiety and mood
  • Pain
  • Energy levels
  • Gastrointestinal issues
  • Inflammation
  • Anxiety and mood
  • Hip dysplasia or arthritis
  • Tumors or growths
  • Improved quality of life

Whew okay now that list is long! We added this one to Olaf’s lineup when he started getting a little aggressive with his siblings. He acts like the alpha male but he was taking it farther than normal. Fighting can be a sign of pain in cats and I definitely wasn’t sitting easy knowing he could be hurting. I mean one of his kidneys was jumbo and the other is undersized couldn’t be the best feeling right?

CBD Pet Oil we Use

Milk Thistle

Scientific studies on milk thistles show that it contain strong anti-inflammatory, antioxidant and detoxifying properties it also promotes cellular regeneration and repair. Should like a miracle drug, no? This herb helps remove toxic chemicals that can accumulate in your cat’s system with renal failure. It is one of the few herbs with no equivalent in conventional medicine!

Milk Thistle we Use

NOTE: This medicine needs to stay refrigerated after opening.


Tripsy helps to maintain a healthy urinary tract. The urinary tract includes the kidneys, bladder and the pathways between them. Now you probably see why this one made the list! However the key feature that appealed to me was that Tripsy is an aid for flushing kidney stones. During a trip to the specialist the vet suggested he thought that our cat had a blockage at the base of the kidney. Now he couldn’t confirm a stone vs. scar tissue vs. something else but I figured why not try.

Tripsy we Buy

NOTE: This medicine needs to stay refrigerated after opening.


When I saw this recommendation I was reminded of how much this helped me when I was battling stomach issues. For those of you unfamiliar with turmeric here is some more information on it.

Turmeric is a spice and herb that has been used for centuries in Ayurvedic (5000 year old holistic health system from India) and Chines medicine.  Turmeric has a distinct yellow color, it is traditionally used as spice in Indian cooking and is also used to enhance the color of mustard in western countries. It is considered to be a super food, and one that can be used for your cat.

So why turmeric for cats with loss of kidney function? It’s a great anti inflammatory which is something we are always looking for with Kidney Disease. A common side affect can be urinary tract infections which are so dangerous in cats. If your cat is anemic this may not be the best route as it is considered a mild anticoagulant.

Turmeric we Buy

NOTE: This medicine needs to stay refrigerated after opening.

Slippery Elm Bark

This powder is pretty magical it works for upset stomachs, mouth ulcers, constipation & diarrhea. And it’s not just for cats, I have a good deal of stomach issues myself and it helps me too!

This natural nausea relief is surprisingly more common than you may think. I was able to pick some up in a pinch at my local grocery store Publix. It was found right in the vitamin aisle. If you want to know how to make your own syrup and to dose go here.

Shop Slipper Elm Bark Powder

Conclusion on Supplements for Cats with Kidney Disease

This concludes our list of supplements for cats with kidney disease. There are a lot of options as you can see and you will want to pick and choose with your vet to find which supplements would help your cat the most. Let us know in the comment section below if your cat with CKD takes any of these supplements (or one we don’t have limited) and if you think they help!


Monday 31st of October 2022

Regarding Azodyl pills and likely any other pills, the Vetoquinol Pill Wrap is simple and works wonderfully. Our little Yoko looks forward very excitedly to her twice-daily doses. -Steve


Thursday 19th of May 2022

Re: KIDNEY RESTORE and KIDNEY SUPPORT GOLD Hi there, just to tell you that my cat who was diagnosed in January with 3rd stage Kidney Failure as been on both of the above products since mid February for one, and since mid March for the other. I give her an oral syringe of the KSG - 5 drops with an organic chicken broth (1cc total) 2X a day, and the KR (1 scoop) into some puréed food and through 2 - 3cc oral syringes 1X a day. She recently had new blood tests done and her IDEX SDMA and Creatinine have normalized. I was actually quite shocked and pleased with the results and will not stop taking either of the kidney products. She looks well, is active for a 13 year old, eats and drinks well...but she now has a heart condition, independent of the kidney issue. All to say that I am pleased to see her looking so well and that I was able to not give her the appetite stimulant pill that was prescribed at the beginning of her DX which made her crazy.

It was because of this site that I learned about both products so I am thankful.. Best, Leslie

Robin Griffin

Friday 20th of May 2022

You have me in tears I am so over joyed to hear that fantastic news! That is wild I have only heard of very few getting back to normal numbers, normally due to an infection and not long term damage to kidneys.


Sunday 13th of March 2022

I purchased the Kidney Restore (also, the Kidney Support Gold whose instructions are far more explicit and clear) but I find it rather odd that the instructions are so "general" and not specific as to how much to give one's pet. After all, a "small" animal is relative....It could be a 6lb. cat or a 10 lb. cat and still be considered "small" and one would assume that the quantity of Kidney Restore would be precise and not general...


Sunday 27th of December 2020

Thanks for the Kidney Restore recommendation. My stage 3 CKD cat has been eating it for about 6 weeks, about half a scoop a day, and his cat-likeness activity is notably much higher now. He doesn’t love the bacon flavor so he usually stops eating the dish that has this mixed in about 75% through, but seeing him jump onto the back of the couch, explore, and chase twist ties on the floor again has been so nice, plus his appetite is better and very few vomits.